Achieving More In Vivo-like Cell Cultures and Better Assays with Permeable Supports
Tuesday, August 14, 2007, 12:00 PM Eastern Time (ET)

For over 30 years, scientist have recognized and taken advantage of culturing cells on permeable supports.  This methodology provides a more in-vivo like environment for the cells and enables the researcher to achieve polarized epithelial or endothelial cell cultures, co-culture of cells separated by a porous membrane, migration and invasion analysis, and a multitude of other applications. One of the more common epithelial models today, Caco-2, form a barrier on permeable supports that can be used to predict intestinal absorption of new chemical entities.  This presentation will focus on cell culture using permeable supports:

Speaker:

Jeanne E. Phillips, Ph.D., has extensive experience in the culture of epithelial cells on permeable support inserts and plates.  She received her graduate degree in Biochemistry from Baylor College of Medicine where she got her start culturing MDCK cells and investigating the ability of these cells to establish polar expression of membrane proteins.  She has also worked extensively in the field of hematology research and prior to joining Corning, she was a Lab Manager at Novartis Institutes for Biomedical Research where she did eADME Preclinical Profiling.  

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